Special Issue: Mass Spectrometric Proteomics

Mass spectrometric-based approaches in quantitative proteomics.

Classically, experiments aimed at studying changes in protein expression have always followed a small set of proteins. This focused approach was necessary since tools to efficiently analyze large numbers of proteins were simply not available. Large-scale quantitative proteomics promises to produce reams of data that previously would have taken decades to measure with classical methods. Mass spe...

Special Issue

Hardware acceleration of processing of mass spectrometric data for proteomics

MOTIVATION High-resolution mass spectrometers generate large data files that are complex, noisy and require extensive processing to extract the optimal data from raw spectra. This processing is readily achieved in software and is often embedded in manufacturers' instrument control and data processing environments. However, the speed of this data processing is such that it is usually performed o...

Special Issue

j Abstract After legislative changes in 1978, Italian psychiatry underwent a thorough overhaul, with the gradual closure of all Mental Hospitals. A nation-wide network of Departments of Mental Health now deliver outpatient and inpatient care, but also run semi-residential and residential facilities (the latter with 2.9 beds per 10,000 inhabitants). Hospital care is delivered through small psych...

Special issue.

It is with great pleasure that I introduce this specia l i s sue of Aging Successfully that focuses on Preventive Gerontology. Aging successfully is dependent on the individual himself or herself. While health professionals can act as a guide through life’s journey, it is only through one’s own efforts that the best outcomes can be assured. This issue provides tools that all of us can use to ag...